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What are milkers nodules primarily associated with?

  1. Sun exposure

  2. Breaks in skin from working with machinery

  3. Breaks in skin in dairy farmers and workers

  4. Viral infections from handling animals

The correct answer is: Breaks in skin in dairy farmers and workers

Milker's nodules are primarily associated with breaks in the skin that occur in dairy farmers and workers. These nodules are a result of direct contact with infected cows or their environments, leading to the transmission of the vaccinia virus, which causes the nodules to form on the skin. The condition typically develops when the skin is compromised, such as through cuts or abrasions, providing an entry point for the virus. This highlights the occupational risk specific to individuals working closely with dairy animals. The nodules themselves are usually painless and can be mistaken for other skin conditions but are distinct in their etiology, emphasizing the importance of safety measures in agricultural work environments. The other choices do not accurately capture the specific association of milkers' nodules with dairy farmers and the nature of their work, which makes option C the most relevant and correct answer.