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What is a primary cause of creeping eruption in humans?

  1. Penetration of skin by infected larvae

  2. Exposure to contaminated water

  3. Inhalation of fungal spores

  4. Direct contact with infected animals

The correct answer is: Penetration of skin by infected larvae

Creeping eruption, also known as cutaneous larva migrans, is primarily caused by the penetration of the skin by the larvae of certain parasites, typically hookworms found in the environment, especially in tropical and subtropical regions. These larvae are often present in soil contaminated with feces and can enter the human body through direct contact with the skin, usually in areas such as the feet. When the larvae penetrate the skin, they cause a characteristic serpentine rash as they migrate through the tissues. This migration is what gives the condition its name, "creeping eruption." It is critical to understand that humans are not suitable hosts for these larvae, which is why they cannot mature or reproduce within the human body; however, their initial entry and movement can lead to significant discomfort and a need for medical treatment. The other options do not accurately describe the primary mechanism of how creeping eruption develops. While exposure to contaminated water can lead to other waterborne diseases or infections, it is not the mechanism for creeping eruption. Inhalation of fungal spores relates to respiratory infections and is unrelated to the skin penetration that causes creeping eruption. Direct contact with infected animals may spread certain zoonotic diseases, but it is not how larvae cause this specific condition. Therefore, the